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AZMango
JAX

Jacksonville Jaguars @ San Francisco 49ers

Any-day matchup, 49ers at home · power ratings as of

SF
Our pick
SFSan Francisco 49ers
55% to win

A probability, not a promise: a 55% pick loses about 4 times in 10.

AZMango model

No market price for this matchup, so there is nothing to compare against.

Advantages Why the 49ers can win

  1. 49ers passing game (2nd in EPA) faces the Jaguars defense that ranks 13th against it.
  2. Simulation: 49ers win 5,530 of 10,000 simulated games.
  3. Travel: Jaguars cross 3 time zones for this one.
  4. Home field: 49ers play at home, worth roughly 1 to 2 points in recent seasons.
  5. History: 49ers won 4 of the last 5 meetings (old results say little about this year's teams).

Disadvantages Why the 49ers may not

  1. Upset odds: Jaguars win 4,470 of 10,000 simulations (45%). A 55% pick still loses about 4 times in 10.
  2. 49ers are missing regulars: WR Mike Evans (out), WR Deebo Samuel Sr. (out).
  3. Turnover margin per game: Jaguars rank 3rd (+0.8), 49ers 21st (-0.4).
  4. Jaguars passing game (4th in EPA) faces the 49ers defense that ranks 14th against it.
  5. Range of outcomes: in the worst 10% of simulations, 49ers lose by 15 or more.

The line and our numbers

MarketAZMango
SpreadNo line yetSF -1.6
Total pointsn/a49.1
Win chanceJAX n/a · SF n/aJAX 45% · SF 55%
Fair moneylineJAX +124 · SF -124

No betting line for this pairing. Odds change all the time, so check a sportsbook before acting on any number here.

10,000 simulated games

  • Typical score: SF 25, JAX 23.
  • 80% of simulations land between JAX by 15 and SF by 18.
See live oddsBetMGM DraftKings FanDuel

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Side by side

JAXSF
4-2Record6-1
25.7 8Points per game28.1 3
17.3 3Points allowed19.9 6
+0.15 3Offense EPA/play+0.19 2
-0.03 11Defense EPA/play allowed-0.03 12
+0.8 3Turnover margin/game-0.4 21
4.5% 24Sacks per dropback5.7% 21

Small numbers are league ranks (1 = best). EPA (expected points added) measures how much each play changes a team's expected score.

Last 5 meetings

DateGameScoreWinnerClosing line
2025-09-282025 Wk 4JAX 26 @ SF 21JAXSF -3.5
2023-11-122023 Wk 10SF 34 @ JAX 3SFSF -3
2021-11-212021 Wk 11SF 30 @ JAX 10SFSF -6.5
2017-12-242017 Wk 16JAX 33 @ SF 44SFJAX -4
2013-10-272013 Wk 8SF 42 @ JAX 10SFSF -16

Basis: power ratings only (no betting line yet). 10,000 drive-by-drive simulations, calibrated so our percentages match how often teams actually won in a 2020-2026 backtest. Model version 1. How it works

No betting line exists for a game that isn't scheduled, so this uses our own power ratings (they pick about 65% of winners in the backtest). Flip home and away