San Francisco 49ers @ Carolina Panthers
Any-day matchup, Panthers at home · power ratings as of
A probability, not a promise: a 64% pick loses about 4 times in 10.
Advantages Why the 49ers can win
- Panthers are missing regulars: CB Akayleb Evans (out), G Damien Lewis (out), LB Jaelan Phillips (out).
- Point differential per game: 49ers rank 3rd (+8.3), Panthers 24th (-2.1).
- 49ers running game (3rd in EPA) faces the Panthers defense that ranks 31st against it.
- Recent scoring margins: worth about 2.3 points to 49ers in our ratings.
- Season-long ratings: over the season, betting lines have rated 49ers about 2.1 points stronger.
Disadvantages Why the 49ers may not
- 49ers are missing regulars: WR Mike Evans (out), WR Deebo Samuel Sr. (out).
- Upset odds: Panthers win 3,650 of 10,000 simulations (36%). A 64% pick still loses about 4 times in 10.
- Travel: 49ers cross 3 time zones for this one.
- Home field: Panthers play at home, worth roughly 1 to 2 points in recent seasons.
- Range of outcomes: in the worst 10% of simulations, 49ers lose by 13 or more.
The line and our numbers
| Market | AZMango | |
|---|---|---|
| Spread | No line yet | SF -4 |
| Total points | n/a | 49.6 |
| Win chance | SF n/a · CAR n/a | SF 64% · CAR 36% |
| Fair moneyline | SF -174 · CAR +174 |
No betting line for this pairing. Odds change all the time, so check a sportsbook before acting on any number here.
10,000 simulated games
- Typical score: CAR 23, SF 27.
- 80% of simulations land between SF by 21 and CAR by 13.
Side by side
| SF | CAR | |
|---|---|---|
| 6-1 | Record | 3-4 |
| 28.1 3 | Points per game | 25.4 9 |
| 19.9 6 | Points allowed | 27.6 27 |
| +0.19 2 | Offense EPA/play | +0.02 13 |
| -0.03 12 | Defense EPA/play allowed | +0.05 23 |
| -0.4 21 | Turnover margin/game | +0.0 16 |
| 5.7% 21 | Sacks per dropback | 4.0% 28 |
Small numbers are league ranks (1 = best). EPA (expected points added) measures how much each play changes a team's expected score.
Last 5 meetings
| Date | Game | Score | Winner | Closing line |
|---|---|---|---|---|
| 2025-11-24 | 2025 Wk 12 | CAR 9 @ SF 20 | SF | SF -7.5 |
| 2022-10-09 | 2022 Wk 5 | SF 37 @ CAR 15 | SF | SF -6 |
| 2019-10-27 | 2019 Wk 8 | CAR 13 @ SF 51 | SF | SF -4.5 |
| 2017-09-10 | 2017 Wk 1 | CAR 23 @ SF 3 | CAR | CAR -4.5 |
| 2016-09-18 | 2016 Wk 2 | SF 27 @ CAR 46 | CAR | CAR -12 |
Basis: power ratings only (no betting line yet). 10,000 drive-by-drive simulations, calibrated so our percentages match how often teams actually won in a 2020-2026 backtest. Model version 1. How it works
No betting line exists for a game that isn't scheduled, so this uses our own power ratings (they pick about 65% of winners in the backtest). Flip home and away