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AZMango
BUF

Buffalo Bills @ Carolina Panthers

Any-day matchup, Panthers at home · power ratings as of

CAR
Our pick
BUFBuffalo Bills
64% to win

A probability, not a promise: a 64% pick loses about 4 times in 10.

AZMango model

No market price for this matchup, so there is nothing to compare against.

Advantages Why the Bills can win

  1. Season-long ratings: over the season, betting lines have rated Bills about 3.3 points stronger.
  2. Panthers are missing regulars: CB Akayleb Evans (out), G Damien Lewis (out), LB Jaelan Phillips (out).
  3. Bills running game (1st in EPA) faces the Panthers defense that ranks 31st against it.
  4. Point differential per game: Bills rank 8th (+4.3), Panthers 24th (-2.1).
  5. Recent form: average margin over the last three games, Bills +1.0, Panthers -9.0.

Disadvantages Why the Bills may not

  1. Panthers passing game (16th in EPA) faces the Bills defense that ranks 29th against it.
  2. Upset odds: Panthers win 3,630 of 10,000 simulations (36%). A 64% pick still loses about 4 times in 10.
  3. Home field: Panthers play at home, worth roughly 1 to 2 points in recent seasons.
  4. Turnover margin per game: Panthers rank 16th (+0.0), Bills 26th (-0.5).
  5. Range of outcomes: in the worst 10% of simulations, Bills lose by 13 or more.

The line and our numbers

MarketAZMango
SpreadNo line yetBUF -3.8
Total pointsn/a52.3
Win chanceBUF n/a · CAR n/aBUF 64% · CAR 36%
Fair moneylineBUF -176 · CAR +176

No betting line for this pairing. Odds change all the time, so check a sportsbook before acting on any number here.

10,000 simulated games

  • Typical score: CAR 24, BUF 27.
  • 80% of simulations land between BUF by 21 and CAR by 13.
See live oddsBetMGM DraftKings FanDuel

Plain links. We are not paid for them and take no bets.

Side by side

BUFCAR
5-1Record3-4
32.8 1Points per game25.4 9
28.5 30Points allowed27.6 27
+0.20 1Offense EPA/play+0.02 13
+0.13 31Defense EPA/play allowed+0.05 23
-0.5 26Turnover margin/game+0.0 16
4.3% 26Sacks per dropback4.0% 28

Small numbers are league ranks (1 = best). EPA (expected points added) measures how much each play changes a team's expected score.

Last 5 meetings

DateGameScoreWinnerClosing line
2025-10-262025 Wk 8BUF 40 @ CAR 9BUFBUF -7
2021-12-192021 Wk 15CAR 14 @ BUF 31BUFBUF -14
2017-09-172017 Wk 2BUF 3 @ CAR 9CARCAR -6.5
2013-09-152013 Wk 2CAR 23 @ BUF 24BUFCAR -3.5
2009-10-252009 Wk 7BUF 20 @ CAR 9BUFCAR -7

Basis: power ratings only (no betting line yet). 10,000 drive-by-drive simulations, calibrated so our percentages match how often teams actually won in a 2020-2026 backtest. Model version 1. How it works

No betting line exists for a game that isn't scheduled, so this uses our own power ratings (they pick about 65% of winners in the backtest). Flip home and away