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AZMango
LA

Los Angeles Rams @ San Francisco 49ers

Any-day matchup, 49ers at home · power ratings as of

SF
Our pick
SFSan Francisco 49ers
54% to win

A probability, not a promise: a 54% pick loses about 5 times in 10.

AZMango model

No market price for this matchup, so there is nothing to compare against.

Advantages Why the 49ers can win

  1. 49ers running game (3rd in EPA) faces the Rams defense that ranks 22nd against it.
  2. Simulation: 49ers win 5,400 of 10,000 simulated games.
  3. Home field: 49ers play at home, worth roughly 1 to 2 points in recent seasons.
  4. Point differential per game: 49ers rank 3rd (+8.3), Rams 12th (+1.6).
  5. Recent scoring margins: worth about 0.9 points to 49ers in our ratings.

Disadvantages Why the 49ers may not

  1. Upset odds: Rams win 4,600 of 10,000 simulations (46%). A 54% pick still loses about 5 times in 10.
  2. 49ers are missing regulars: WR Mike Evans (out), WR Deebo Samuel Sr. (out).
  3. Season-long ratings: over the season, betting lines have rated Rams about 1.3 points stronger.
  4. Range of outcomes: in the worst 10% of simulations, 49ers lose by 15 or more.
  5. Weak spot: 49ers rank 30th in field goal percentage (66.7%).

The line and our numbers

MarketAZMango
SpreadNo line yetSF -1.5
Total pointsn/a50.6
Win chanceLA n/a · SF n/aLA 46% · SF 54%
Fair moneylineLA +117 · SF -117

No betting line for this pairing. Odds change all the time, so check a sportsbook before acting on any number here.

10,000 simulated games

  • Typical score: SF 26, LA 24.
  • 80% of simulations land between LA by 15 and SF by 18.
See live oddsBetMGM DraftKings FanDuel

Plain links. We are not paid for them and take no bets.

Side by side

LASF
3-4Record6-1
24.3 11Points per game28.1 3
22.7 16Points allowed19.9 6
+0.06 10Offense EPA/play+0.19 2
-0.06 5Defense EPA/play allowed-0.03 12
-0.7 29Turnover margin/game-0.4 21
4.2% 27Sacks per dropback5.7% 21

Small numbers are league ranks (1 = best). EPA (expected points added) measures how much each play changes a team's expected score.

Last 5 meetings

DateGameScoreWinnerClosing line
2026-09-102026 Wk 1SF 27 @ LA 7SFLA -3.5
2025-11-092025 Wk 10LA 42 @ SF 26LALA -5.5
2025-10-022025 Wk 5SF 26 @ LA 23SFLA -8.5
2024-12-122024 Wk 15LA 12 @ SF 6LASF -3
2024-09-222024 Wk 3SF 24 @ LA 27LASF -6

Basis: power ratings only (no betting line yet). 10,000 drive-by-drive simulations, calibrated so our percentages match how often teams actually won in a 2020-2026 backtest. Model version 1. How it works

No betting line exists for a game that isn't scheduled, so this uses our own power ratings (they pick about 65% of winners in the backtest). Flip home and away